Title: Top Santa María Department Hotels: 2026 Best Hotels in Santa María Department - Expedia.com

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## Check prices for these dates

Tonight

[Mar 12 - Mar 13](https://www.expedia.com/Hotel-Search?regionId=553248635975751146&startDate=2026-03-12&endDate=2026-03-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 13 - Mar 14](https://www.expedia.com/Hotel-Search?regionId=553248635975751146&startDate=2026-03-13&endDate=2026-03-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248635975751146&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=553248635975751146&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa María Department hotels

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95740000/95733400/95733324/735a6640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/96000000/95740000/95733400/95733324/6c0e54e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/96000000/95740000/95733400/95733324/8bf5aa3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95740000/95733400/95733324/f77407d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Eco Glamping Amaicha del Valle

[](https://www.expedia.com/Amaicha-Del-Valle-Hotels-Eco-Glamping-Amaicha-Del-Valle.h95733324.Hotel-Information)

Amaicha del Valle

$176 nightly

$176 total

Mar 13 - Mar 14

[](https://www.expedia.com/Amaicha-Del-Valle-Hotels-Eco-Glamping-Amaicha-Del-Valle.h95733324.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342849/a8c893d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342849/9d5e0292.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342849/43d9e583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342849/11188a87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabaña Achalay 1 – Refugio en Santa María

[](https://www.expedia.com/Santa-Maria-Hotels-Cabana-Achalay-1-Refugio-En-Santa-Maria.h116342849.Hotel-Information)

Santa María

$86 nightly

$86 total

Mar 13 - Mar 14

[](https://www.expedia.com/Santa-Maria-Hotels-Cabana-Achalay-1-Refugio-En-Santa-Maria.h116342849.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/117000000/116230000/116221600/116221596/bc02d8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/117000000/116230000/116221600/116221596/00f83e17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, coffee/tea maker](https://images.trvl-media.com/lodging/117000000/116230000/116221600/116221596/7528be11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116230000/116221600/116221596/e17f651f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Esmeralda: the star accommodation in Amaicha del Valle

[](https://www.expedia.com/Amaicha-Del-Valle-Hotels-La-Esmeralda-The-Star-Accommodation-In-Amaicha-Del-Valle.h116221596.Hotel-Information)

Amaicha del Valle

$78 nightly

$78 total

Mar 14 - Mar 15

[](https://www.expedia.com/Amaicha-Del-Valle-Hotels-La-Esmeralda-The-Star-Accommodation-In-Amaicha-Del-Valle.h116221596.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/114000000/113970000/113962900/113962887/67626ca8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/tub, towels, soap, shampoo](https://images.trvl-media.com/lodging/114000000/113970000/113962900/113962887/7a040ec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/114000000/113970000/113962900/113962887/ab3d4d9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/114000000/113970000/113962900/113962887/5c462c09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Boutique Altos de Amaicha

[](https://www.expedia.com/Amaicha-Del-Valle-Hotels-Hotel-Boutique-Altos-De-Amaicha.h113962887.Hotel-Information)

Amaicha Del Valle

[](https://www.expedia.com/Amaicha-Del-Valle-Hotels-Hotel-Boutique-Altos-De-Amaicha.h113962887.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/117000000/116230000/116221700/116221625/6486b328.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116230000/116221700/116221625/5e8a57d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/117000000/116230000/116221700/116221625/7c51ec70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, internet, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/117000000/116230000/116221700/116221625/1f36d62a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cerco del Trigo. Total peace

[](https://www.expedia.com/Amaicha-Del-Valle-Hotels-Vrbo-Property.h116221625.Hotel-Information)

Amaicha del Valle

$101 nightly

$101 total

Mar 14 - Mar 15

[](https://www.expedia.com/Amaicha-Del-Valle-Hotels-Vrbo-Property.h116221625.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342882/5dd5d6b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342882/eaf6dd15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, internet, bed sheets](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342882/2eef2b49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/117000000/116350000/116342900/116342882/832c81a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabaña Achalay 1 – Refugio en Santa María

[](https://www.expedia.com/Santa-Maria-Hotels-Cabana-Achalay-1-Refugio-En-Santa-Maria.h116342882.Hotel-Information)

Santa María

$86 nightly

$86 total

Mar 13 - Mar 14

[](https://www.expedia.com/Santa-Maria-Hotels-Cabana-Achalay-1-Refugio-En-Santa-Maria.h116342882.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Santa María Department Hotel Reviews

![Patios de Cafayate - Wine Hotel & Restaurant](https://images.trvl-media.com/lodging/2000000/1330000/1322200/1322111/b4b3fdad_y.jpg)

### Patios de Cafayate - Wine Hotel & Restaurant

10/10 Excellent

"The room was spacious & well equipped. The pool area was very inviting & the dining room very good."

[](https://expedia.com/Cafayate-Hotels-Patios-De-Cafayate-Wine-Hotel.h1322111.Hotel-Information)

![Hosteria La Angostura](https://images.trvl-media.com/lodging/105000000/104540000/104533900/104533890/0c55665c_y.jpg)

### Hosteria La Angostura

6/10 Okay

"Property was nice but there was some confusion at check in. I pre paid though Expedia but upon walking to our room I was told my credit card didn’t work but they had someone else credit card on my file. It was very odd. I didn’t end up getting charged extra but it seemed alittle odd. Also our booking said checkout was 11 am and they told us checkout was 10 am. Not sure if this was Expedia’s issue or the hotels. The property was nice and in a beautiful location. We loved the dogs. But the room are very echoing and you can really hear your neighbours. Over all would stay again though. Just made sure you are aware of your booking records. "

[](https://expedia.com/El-Mollar-Hotels-Hosteria-La-Angostura.h104533890.Hotel-Information)

![Altalaluna Hotel Boutique & Spa](https://images.trvl-media.com/lodging/16000000/15370000/15361300/15361271/03adbecb_y.jpg)

### Altalaluna Hotel Boutique & Spa

8/10 Good

"A very nice, high quality hotel. The rates are a bit steep for Argentina, but it is worth it. It is quite distant from the next town, so not much to do other than relaxing and enjoying the tranquility of the place. The restaurant is good and there is a nice swiming pool "

[](https://expedia.com/Cafayate-Hotels-Altalaluna-Hotel-Boutique-Spa.h15361271.Hotel-Information)

![Iraola Hotel Boutique](https://images.trvl-media.com/lodging/109000000/108750000/108740500/108740402/d5e4e5c0_y.jpg)

### Iraola Hotel Boutique

10/10 Excellent

"Simply lovely"

[](https://expedia.com/Cafayate-Hotels-Iraola-Hotel-Boutique.h108740402.Hotel-Information)

![El Porvenir Wine Lodge](https://images.trvl-media.com/lodging/104000000/103570000/103566700/103566671/26248c90_y.jpg)

### El Porvenir Wine Lodge

10/10 Excellent

"Everything was perfect. The setting was spectacular. "

[](https://expedia.com/Cafayate-Hotels-El-Porvenir-Wine-Lodge.h103566671.Hotel-Information)

![VIEJA POSADA HOTEL HISTORICO](https://images.trvl-media.com/lodging/93000000/92400000/92391900/92391824/bb908147_y.jpg)

### VIEJA POSADA HOTEL HISTORICO

10/10 Excellent

"Beautiful setting/decor at great downtown location, with nice restaurant and friendly, helpfull staff"

[](https://expedia.com/Cafayate-Hotels-VIEJA-POSADA-HOTEL-HISTORICO.h92391824.Hotel-Information)

![Hotel Portal del Santo](https://images.trvl-media.com/lodging/5000000/4470000/4461000/4460915/382e6f00_y.jpg)

### Hotel Portal del Santo

10/10 Excellent

"Very friendly helpful staff "

[](https://expedia.com/Cafayate-Hotels-Hotel-Portal-Del-Santo.h4460915.Hotel-Information)

![HOTEL PLAZA CAFAYATE](https://images.trvl-media.com/lodging/112000000/111210000/111207700/111207630/0814b150_y.jpg)

### HOTEL PLAZA CAFAYATE

10/10 Excellent

"As always excellent service, clean rooms and super nice and helpful staff. "

[](https://expedia.com/Cafayate-Hotels-HOTEL-PLAZA-CAFAYATE.h111207630.Hotel-Information)

![Piattelli Wine Resort](https://images.trvl-media.com/lodging/85000000/84400000/84390700/84390617/b92a016b_y.jpg)

### Piattelli Wine Resort

10/10 Excellent

"Staff great and it is beautiful setting. Dinner with pork and a beet salad delicious, and breakfast also plentiful options. The room is large and has fireplace and balcony. Need more floor mats so not slip in shower. Tried massage and shout out to Susanna (who was better than other masseuse I had). Very relaxing stay. "

[](https://expedia.com/Cafayate-Hotels-Piattelli-Wine-Resort.h84390617.Hotel-Information)

## Explore a world of travel with Expedia

- Explore a world of travel with Expedia

### Top cities in Santa María Department

- [Santa Maria Hotels ](https://expedia.com/Santa-Maria-Hotels.d6348211.Travel-Guide-Hotels)
- [Casa de Piedra Hotels ](https://expedia.com/Casa-De-Piedra-Hotels.d553248635924012533.Travel-Guide-Hotels)
- [Loro Huasi Hotels ](https://expedia.com/Loro-Huasi-Hotels.d553248635924012675.Travel-Guide-Hotels)
- [Fuerte Quemado Hotels ](https://expedia.com/Fuerte-Quemado-Hotels.d553248635924012235.Travel-Guide-Hotels)

### Hotels near popular Attractions

- [Hotels near Bodega El Esteco ](https://expedia.com/Bodega-El-Esteco-Hotels.0-l553248621532463836-0.Travel-Guide-Filter-Hotels)
- [Hotels near Cafayate Church ](https://expedia.com/Cafayate-Church-Hotels.0-l6097378-0.Travel-Guide-Filter-Hotels)
- [Hotels near Plaza de Cafayate ](https://expedia.com/Plaza-De-Cafayate-Hotels.0-l6097380-0.Travel-Guide-Filter-Hotels)
- [Hotels near Vasija Secreta Winery ](https://expedia.com/Vasija-Secreta-Winery-Hotels.0-l553248621532463833-0.Travel-Guide-Filter-Hotels)
- [Hotels near Domingo Hermanos Winery ](https://expedia.com/Domingo-Hermanos-Winery-Hotels.0-l553248621532463834-0.Travel-Guide-Filter-Hotels)
- [Hotels near La Estancia De Cafayate Golf Course ](https://expedia.com/La-Estancia-De-Cafayate-Golf-Course-Hotels.0-l553248621562511828-0.Travel-Guide-Filter-Hotels)
- [Hotels near Bodega El Porvenir de Cafayate ](https://expedia.com/Bodega-El-Porvenir-De-Cafayate-Hotels.0-l553248621532463838-0.Travel-Guide-Filter-Hotels)
- [Hotels near Rio Colorado Waterfall ](https://expedia.com/Rio-Colorado-Waterfall-Hotels.0-l553248621532370131-0.Travel-Guide-Filter-Hotels)
- [Hotels near Tafi del Valle Church ](https://expedia.com/Tafi-Del-Valle-Church-Hotels.0-l6280005-0.Travel-Guide-Filter-Hotels)
- [Hotels near Etchart Winery ](https://expedia.com/Etchart-Winery-Hotels.0-l553248621532370126-0.Travel-Guide-Filter-Hotels)

### Explore more hotels

- [Patios de Cafayate - Wine Hotel & Restaurant ](https://expedia.com/Cafayate-Hotels-Patios-De-Cafayate-Wine-Hotel.h1322111.Hotel-Information)
- [Piattelli Wine Resort ](https://expedia.com/Cafayate-Hotels-Piattelli-Wine-Resort.h84390617.Hotel-Information)
- [Iraola Hotel Boutique ](https://expedia.com/Cafayate-Hotels-Iraola-Hotel-Boutique.h108740402.Hotel-Information)
- [El Porvenir Wine Lodge ](https://expedia.com/Cafayate-Hotels-El-Porvenir-Wine-Lodge.h103566671.Hotel-Information)
- [VIEJA POSADA HOTEL HISTORICO ](https://expedia.com/Cafayate-Hotels-VIEJA-POSADA-HOTEL-HISTORICO.h92391824.Hotel-Information)
- [Hotel Asturias ](https://expedia.com/Cafayate-Hotels-Hotel-Asturias.h3489185.Hotel-Information)
- [HOTEL PLAZA CAFAYATE ](https://expedia.com/Cafayate-Hotels-HOTEL-PLAZA-CAFAYATE.h111207630.Hotel-Information)
- [Buena Vid by Chadel Management ](https://expedia.com/Cafayate-Hotels-Buena-Vid-By-Chadel-Management.h101920087.Hotel-Information)
- [Hosteria La Angostura ](https://expedia.com/El-Mollar-Hotels-Hosteria-La-Angostura.h104533890.Hotel-Information)
- [Hotel Cafayate ](https://expedia.com/Cafayate-Hotels-Hotel-Cafayate.h117152667.Hotel-Information)

[See a list of all hotels in Santa María Department](https://expedia.com/All-Santa-Maria-Department-Hotels.d553248635975751146.Travel-Guide-City-All-Hotels)

### More ways to book

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